HUTOX 100

Hutox 100 Units (Botulinum Toxin Type A)

Hutox 100 Units is a premium, vacuum-dried Botulinum Toxin Type A injectable manufactured in South Korea by Huons BioPharma. Utilizing advanced purification protocols, Hutox delivers highly consistent neuromuscular relaxation, making it a trusted choice for global aesthetic clinicians specializing in targeted wrinkle reduction and localized therapeutic treatments.

By temporarily intercepting signal pathways at the neuromuscular junction, Hutox effectively relaxes dynamic muscle groups, smoothing out deep-set facial lines while retaining natural, soft expressions when administered precisely.

Technical Specifications & Composition

Primary Clinical Indications

Hutox 100U is engineered for high precision, minimizing product diffusion to ensure localized efficacy. It is primarily indicated for:

• Dynamic Wrinkle Correction: Softening moderate-to-severe glabellar (frown) lines, prominent forehead creases, and lateral canthal lines (crow’s feet).

• Facial Contouring: Relaxing the masseter muscle to soften the jawline.

• Hyperhidrosis Management: Managing excessive focal sweating in the palmar, plantar, and axillary (underarm) regions by blocking acetylcholinergic stimulation of sweat glands.

Mechanism of Action

Once introduced into the targeted muscle tissue, the neurotoxin complex binds to peripheral cholinergic nerve endings. It inhibits the exocytosis of acetylcholine, the principal neurotransmitter responsible for muscle contractions. As local muscle activity temporarily diminishes, the overlying skin surface relaxes, allowing wrinkles to smooth out over time.

• Initial Onset: Visible improvements typically begin surfacing within 2 to 5 days.

• Peak Efficacy: Full stabilizing results manifest around the 1 to 2-week mark.

• Duration: Clinical effects routinely persist for 4 to 6 months, varying slightly based on individual patient metabolism and muscle volume.

Reconstitution & Administration Protocol

Hutox 100 Units is intended strictly for professional use by licensed healthcare practitioners.

Dilution Guidelines

To achieve a standard clinical concentration of 4 Units per 0.1 mL, reconstitute the vacuum-dried cake using 2.5 mL of sterile, preservative-free 0.9% sodium chloride (saline) solution.

Administration Steps

1. Introduce the saline slowly into the vial, allowing the vacuum to draw it in gently.

2. Swirl the vial softly to completely dissolve the lyophilized powder. Do not shake violently, as mechanical agitation can denature the biological proteins.

3. Utilizing a sterile 30-gauge needle, inject 0.1 mL (4 U) across the designated treatment points (e.g., standard 5-point intramuscular injection pattern for the glabella complex involving the corrugator and procerus muscles).

Storage, Stability, & Handling

• Unopened Vials: Store constantly in a secure refrigerator at a temperature between 2°C and 8°C. The sealed product maintains chemical stability for up to 36 months from the date of manufacture.

• Post-Reconstitution: Once the solution is mixed with saline, it is highly recommended to use it immediately or within a strict 24-hour window, keeping the drawn syringe refrigerated at 2–8°C in the interim.