$35.00
Minimum order $400
Free shipping $600
Some dermal fillers promise volume correction but fall short under scrutiny. Rejeunesse Deep is different. Manufactured by Newmedic Co., Ltd. in South Korea, this high-density, cross-linked hyaluronic acid (HA) filler.
It is designed for medium-to-deep wrinkles, pronounced facial folds, and contouring procedures. Results that may last between 12 and 18 months per clinical observations. With a concentration of 24 mg/mL of non-animal HA and 0.3% lidocaine hydrochloride, it addresses two things at once: visible correction and patient comfort.
The filler is formulated through Newmedic’s proprietary UPHEC purification technology, a process that keeps endotoxin levels below 1.2 EU/mL and leaves no detectable BDDE residue.
That combination matters clinically — it reduces the risk of immunogenic reactions and post-treatment edema. For practitioners looking for a reliable, long-lasting Korean dermal filler that meets CE standards, Rejeunesse Deep is worth understanding in detail.
| Parameter | Details |
| HA Concentration | 24 mg/mL |
| Lidocaine | 0.3% hydrochloride |
| Volume | 1.1 mL per prefilled syringe |
| Needle | 2 × 27G |
| Injection Depth | Mid to deep dermis / subcutaneous |
| Duration | 12–18 months (typical range) |
| Shelf Life | 24 months from manufacturing date |
| Storage | 2–25°C, away from direct sunlight |
| Manufacturer | Newmedic Co., Ltd., South Korea |
| Certifications | CE, GMP, ISO 9001, ISO 13485 |
Rejeunesse Deep is a monophasic, sterile, pyrogen-free viscoelastic gel. “Monophasic” means the HA particles are uniformly distributed throughout the gel — a structural characteristic that contributes to consistent injection force and stable results after placement.
The cross-linking agent BDDE (1,4-butanediol diglycidyl ether) bonds the HA chains together, which is what gives the filler its density and resistance to enzymatic breakdown.
Crucially, the manufacturing process removes all detectable BDDE residue from the final product, which is a meaningful safety distinction. Residual cross-linker in some fillers has been associated with increased tissue reactions; Rejeunesse Deep avoids that concern.
UPHEC (Ultra-Purified High-Efficiency Cross-linking) is Newmedic’s proprietary purification process. It removes endotoxins and impurities from the HA matrix with a thoroughness that keeps final endotoxin levels below 1.2 EU/ml. Lower endotoxin burden translates directly to reduced risk of post-injection inflammation — a practical benefit for both practitioners and patients.
Rejeunesse Deep undergoes both aseptic filling and terminal sterilization — a dual-stage process that adds an additional layer of microbiological safety beyond single-sterilization methods. The result is a product that is genuinely pyrogen-free and free of contaminants at the point of use.
Rejeunesse Deep is indicated for mid-to-deep dermis and subcutaneous injection, making it appropriate for structural correction rather than surface-level hydration. Clinical applications include:
For more substantial structural correction, such as significant cheek or chin augmentation, Rejeunesse Shape may be the more suitable option. It is typically used with a 26G needle and placed deeper in the subcutaneous layer.
Practitioners frequently use both Deep and Shape together depending on treatment goals. For comparison: Rejeunesse Fine targets superficial lines with a 30G needle, while Sparkle addresses the most superficial skin hydration layer.
At 0.3% concentration, lidocaine hydrochloride is included at a level that provides meaningful pain reduction during injection without clinically significant systemic effects.
Numbing typically sets in within the first few minutes of injection and can last roughly one to two hours — long enough to cover the procedure and immediate recovery.
For practitioners, this reduces the reliance on topical anesthetic application before treatment. For patients, it lowers anxiety around needle procedures, which can improve cooperation and overall experience.
The lidocaine formulation is standard across the Rejeunesse product range.
Results may last between 12 and 18 months in typical cases, though individual variation applies. Duration depends on several factors.
These include the treatment area, injection depth, the volume used, and the patient’s individual metabolism. Areas with more movement, such as the lips, may break down filler more quickly.
Rejeunesse Deep has a well-documented safety profile grounded in its manufacturing purity. That said, as with all injectable dermal fillers, there are contraindications that practitioners must screen for before treatment:
Common post-treatment effects — redness, swelling, mild tenderness — are generally temporary and typically resolve within 3 to 7 days. Applying an ice pack briefly to the injection site can help manage initial swelling. Patients should avoid sun exposure and heavy exercise for at least 24 hours following treatment.
This product is intended for professional use only by trained and certified medical practitioners. Self-injection is not recommended and carries significant health and aesthetic risks.
Rejeunesse Deep has passed an on-site inspection by the US FDA and holds CE certification (Europe), GMP, ISO 9001, and ISO 13485 certifications. Practitioners should verify current regulatory status in their specific jurisdiction, as approval status can differ between markets.
Both fillers contain 24 mg/mL HA and 0.3% lidocaine in 1.1 mL syringes. The key differences lie in particle size and injection depth. Deep uses a 27G needle and targets the mid-to-deep dermis, making it suitable for moderate wrinkles and lip work.
Shape uses a 26G needle, which has a larger bore for the thicker gel. It injects deeper into the subcutaneous layer, making it better suited for significant volumizing of the cheeks, chin, and nose. For treatment of deep folds combined with contouring, some practitioners use both.
Volume correction is generally visible immediately following the procedure. However, initial swelling may temporarily affect the appearance, so it’s best to assess the final settled result after 2 to 3 days.
Full results are usually apparent within one week.
Yes — unlike Rejeunesse Shape, the Rejeunesse Deep formulation is compatible with hyaluron pen delivery. However, hyaluron pen application is not ideal for superficial lines or wrinkles; it is better suited for volumizing procedures.
Store at 2–25°C. Do not freeze or expose to direct sunlight. Avoid applying pressure or force to the syringe during storage. The product is for single use only — discard after the procedure. Shelf life is 24 months from the manufacturing date printed on the packaging.
⚠ For Professional Use Only
Licensed professionals with appropriate training must administer Rejeunesse Deep dermal filler. This description provides general information and does not replace medical consultation. Results may vary, and KBeautyPharm disclaims liability for harm from self-injection.
Join thousands of clinics, beauty practitioners, and distributors who trust K Beauty Pharm as their go-to Aesthetics Supplier. Experience why our injectables are the global standard for safety, quality, and innovation. Join a growing network of professionals who value:
